On February 15, 2004, the Rangers traded Rodriguez to the New York Yankees for second baseman Alfonso Soriano and a player to be named later ( Joaquín Árias was sent to the Rangers on March 24). The Rangers also agreed to pay $67 million of the $179 million left on Rodriguez's contract. Rodriguez agreed to switch positions from shortstop to third base, paving the way for the trade, because the popular Derek Jeter was already entrenched at shortstop. Rodriguez also had to switch uniform numbers, from 3 to 13; he had worn 3 his entire career, but that number is retired by the Yankees in honor of Babe Ruth .
As with other topically administered ophthalmic drugs, VEXOL® 1% (rimexolone ophthalmic suspension) is absorbed systemically. Studies in normal volunteers dosed bilaterally once every hour during waking hours for one week have demonstrated serum concentrations ranging from less than 80 pg/mL to 470 pg/mL. The mean serum concentrations were approximately 130 pg/mL. Serum concentrations were at or near steady state after 5 to 7 hourly doses. After decreasing the dosing frequency to once every two hours while awake during the second week of administration, mean serum concentrations were approximately 100 pg/mL.