Corticosteroid myopathy presents as weakness and wasting of the proximal limb and girdle muscles and is generally reversible following cessation of therapy.
Corticosteroids inhibit intestinal calcium absorption and increase urinary calcium excretion leading to bone resorption and bone loss. Bone loss of 3% over one year has been demonstrated with prednisolone 10 mg per day. Postmenopausal females are particularly at risk for loss of bone density. Sixteen percent of elderly patients treated with corticosteroids for 5 years may experience vertebral compression fractures. One author reported measurable bone loss over two years in women on concomitant therapy with prednisolone mg per day and tamoxifen. [ Ref ]
Some side effects that may occur when using FLONASE ® , a nasal steroid, include burning, dryness, crusting, or other irritation inside the nose. 3 Other possible side effects of FLONASE ® include occasional nose bleeds, nasal whistling, and headaches. 4 If you experience symptoms while using FLONASE ® that resemble an allergic reaction such as rash, swelling of the face or tongue, wheezing, or feeling faint, stop using FLONASE ® and see a doctor. 4 If you have questions or concerns about symptoms or trouble using the medication it is best to call your doctor.