CLOBEX ® Spray can pass through your skin. Too much CLOBEX ® Spray passing through your skin can shut down your adrenal glands. This usually happens if you use too much CLOBEX ® Spray, or you use it for too long. If this happens, your adrenal glands may not start working immediately once you stop using CLOBEX ® Spray. Shutting down of the adrenal glands can cause nausea, vomiting, fever, low blood pressure, heart attack, and even death because your body cannot respond to stress or illness. Your doctor may do special blood and urine tests to check your adrenal gland function while you are using CLOBEX ® Spray.