Double vision steroid treatment

Multiple sclerosis is a disease of the central nervous system that can gradually affect a patient’s vision. As the condition progresses and wears away the protective covering of the nerves, the nerves become damaged and inflamed. Patients may experience blurred vision, eye pain, loss of color vision or total loss of vision. Treatment for vision problems associated with multiple sclerosis may vary depending on the severity of the condition. Some cases will improve on their own, while others may benefit from steroid medication to reduce inflammation and expedite the healing process.

Difluprednate has been shown to be embryotoxic (decrease in embryonic body weight and a delay in embryonic ossification) and teratogenic (cleft palate and skeletal anomalies) when administered subcutaneously to rabbits during organogenesis at a dose of 1-10 mcg/kg/day. The no-observed-effect-level (NOEL) for these effects was 1 mcg/kg/day, and 10 mcg/kg/day was considered to be a teratogenic dose that was concurrently found in the toxic dose range for fetuses and pregnant females. Treatment of rats with 10 mcg/kg/day subcutaneously during organogenesis did not result in any reproductive toxicity, nor was it maternally toxic. At 100 mcg/kg/day after subcutaneous administration in rats, there was a decrease in fetal weights and delay in ossification, and effects on weight gain in the pregnant females. It is difficult to extrapolate these doses of difluprednate to maximum daily human doses of Durezol, since Durezol is administered topically with minimal systemic absorption, and difluprednate blood levels were not measured in the reproductive animal studies. However, since use of difluprednate during human pregnancy has not been evaluated and cannot rule out the possibility of harm, Durezol should be used during pregnancy only if the potential benefit justifies the potential risk to the embryo or fetus.

  • Keep the tablets in a safe place, out of the reach of children.
  • If your doctor decides to stop the treatment, return any remaining tablets to the pharmacist. Do not flush them down the toilet or throw them away.
  • Tell your doctor if you are sick just after taking a tablet, as you may need to take another one.
  • If you forget to take your tablet, do not take a double dose. Ask your doctor or nurse for advice.
  • If you're having a short course of steroids as part of your treatment, do not get more from your GP.

Double vision steroid treatment

double vision steroid treatment

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